Abstract
Two new compounds, penicillone A (1) and penicillactam (2), were isolated together with 17 known compounds from a marine-derived fungus Penicillium sp. F11. The structures of the new compounds as well as a firstly literatural reported known compound (3) were assigned by spectroscopic methods including 1D/2D NMR and MS analysis techniques. Their cytotoxicities against HT1080, Cne2, and Bel7402 cell lines were also evaluated.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / isolation & purification*
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Antineoplastic Agents / pharmacology
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Drug Screening Assays, Antitumor
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Humans
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Marine Biology
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Penicillium / chemistry*
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Pyrones / chemistry
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Pyrones / isolation & purification*
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Pyrones / pharmacology
Substances
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Antineoplastic Agents
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Pyrones
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penicillactam
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penicillone A