Granulomatous myositis associated with brucellosis: a case report and literature review

Muscle Nerve. 2012 Feb;45(2):290-3. doi: 10.1002/mus.22261.

Abstract

Brucellosis, a multisystem infectious disorder, continues to be a serious public health problem in some parts of the world. Neurobrucellosis constitutes about 4% of all brucellosis cases. Brucellosis-associated myositis is extremely rare, and there is only 1 reported case in the English literature. We report a 16-year-old boy with subacute, fluctuating, progressive muscle pain, with tenderness, swelling, and diffuse, asymmetric weakness. He also had significantly elevated serum Brucella titers and a muscle biopsy showed inflammatory granulomatous myositis. We review the literature on myositis associated with brucellosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Action Potentials / physiology
  • Adolescent
  • Antibodies, Antineutrophil Cytoplasmic / metabolism
  • Brucella
  • Brucellosis / complications*
  • Humans
  • Male
  • Muscle, Skeletal / physiopathology
  • Myositis / complications*
  • Myositis / microbiology
  • Myositis / physiopathology
  • Neural Conduction / physiology

Substances

  • Antibodies, Antineutrophil Cytoplasmic