Biofunctional nanosystems based on dendritic polymers

J Control Release. 2012 Jul 20;161(2):484-95. doi: 10.1016/j.jconrel.2011.12.040. Epub 2012 Jan 5.

Abstract

Among the various polymeric architectures, dendritic polymers have received a substantial scientific focus for their highly branched, multifunctional, and well-defined structures. Dendritic scaffolds have found many applications for designing nanoscale drug/gene delivery carriers and constructing diagnostic and biosensor devices, and protein-resistant surfaces. A significant number of research groups across Europe share the common objective, yet in conspicuously individual ways, of utilizing such polymers for devising innovative biomedical tools and techniques. This review describes the European effort of finding the application of dendritic polymers as advanced generation therapeutics within the purview of nanomedicine.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents
  • Dendrimers / therapeutic use*
  • Drug Delivery Systems*
  • Gene Transfer Techniques*
  • Humans
  • Nanoparticles / therapeutic use*

Substances

  • Anti-Inflammatory Agents
  • Dendrimers