Polymerase chain reaction-based ganciclovir resistance testing of ocular fluids for cytomegalovirus retinitis

Arch Ophthalmol. 2012 Jan;130(1):113-5. doi: 10.1001/archophthalmol.2011.380.
No abstract available

Publication types

  • Case Reports
  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Antiviral Agents / therapeutic use
  • Aqueous Humor / virology*
  • Cytomegalovirus / genetics*
  • Cytomegalovirus / isolation & purification
  • Cytomegalovirus Retinitis / drug therapy
  • Cytomegalovirus Retinitis / virology*
  • DNA, Viral / analysis
  • DNA-Directed DNA Polymerase / genetics
  • Drug Resistance, Viral / genetics*
  • Female
  • Foscarnet / therapeutic use
  • Ganciclovir / analogs & derivatives
  • Ganciclovir / therapeutic use*
  • Genome, Viral / genetics
  • Genotype
  • Humans
  • Infant
  • Male
  • Phosphotransferases (Alcohol Group Acceptor) / genetics
  • Point Mutation*
  • Polymerase Chain Reaction
  • Retrospective Studies
  • Valganciclovir
  • Viral Proteins / genetics
  • Vitreous Body / virology*

Substances

  • Antiviral Agents
  • DNA, Viral
  • UL54 protein, Human herpesvirus 5
  • Viral Proteins
  • Foscarnet
  • Phosphotransferases (Alcohol Group Acceptor)
  • ganciclovir kinase
  • DNA-Directed DNA Polymerase
  • Valganciclovir
  • Ganciclovir