Abstract
The characterization of a polyelectrolyte complex material comprised of two biopolymers, a chitosan upper layer and a gellan gum under layer, is reported. It is shown that the upper layer of chitosan with incorporated levofloxacin displays an antibacterial activity, while the under layer of a gellan gum/TiO(2) composite supports the growth of fibroblastic cells.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology
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Biocompatible Materials / chemical synthesis*
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Biocompatible Materials / pharmacology
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Cell Proliferation / drug effects
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Cell Survival / drug effects
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Chitosan / chemistry*
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Drug Compounding
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Escherichia coli / drug effects
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Fibroblasts / cytology
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Fibroblasts / drug effects
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Levofloxacin*
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Microbial Viability / drug effects
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Ofloxacin / chemistry
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Ofloxacin / pharmacology*
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Polysaccharides, Bacterial / chemistry*
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Titanium / chemistry
Substances
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Anti-Bacterial Agents
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Biocompatible Materials
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Polysaccharides, Bacterial
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titanium dioxide
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Levofloxacin
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gellan gum
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Chitosan
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Ofloxacin
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Titanium