[A case of lung metastases after surgery for colon cancer demonstrating complete response for more than six years after treatment with UFT/LV]

Gan To Kagaku Ryoho. 2011 Nov;38(12):2520-2.
[Article in Japanese]

Abstract

A 54-year-old female with cecal cancer underwent Rt. hemicolectomy in December 2000. The lesion was mod, ss, p1(+), n1, stage IV. The level of CEA increased around August 2002. Abdominal CT revealed a recurrent tumor in the RLQ in July 2003, peritoneal dissemination was suspected. In December 2003, we performed a partial resection of the ileum and transverse colon including initial anastomosis. Lung metastases were found by chest CT in right S4, S5, S9 and S3, S8 in February 2004. Because of experience of severe side effect of intravenous chemotherapy, UFT/LV was administered from February 2004. Chest CT revealed the disappearance of tumor in September 2004, and no signs of recurrence were observed for 65 months.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Colonic Neoplasms / drug therapy*
  • Colonic Neoplasms / pathology
  • Colonic Neoplasms / surgery
  • Female
  • Humans
  • Leucovorin / administration & dosage
  • Leucovorin / therapeutic use*
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / secondary
  • Middle Aged
  • Neoplasm Staging
  • Recurrence
  • Remission Induction
  • Tegafur / administration & dosage
  • Tegafur / therapeutic use
  • Time Factors
  • Tomography, X-Ray Computed
  • Uracil / administration & dosage
  • Uracil / therapeutic use

Substances

  • Tegafur
  • Uracil
  • Leucovorin

Supplementary concepts

  • 1-UFT protocol