Distribution of estimated glomerular filtration rate (eGFR) values in patients receiving contrast-enhanced magnetic resonance imaging

Jpn J Radiol. 2012 Feb;30(2):116-9. doi: 10.1007/s11604-011-0019-6. Epub 2011 Dec 27.

Abstract

Purpose: The aim of this study was to elucidate the distribution of estimated glomerular filtration rate (eGFR) values in patients who underwent gadolinium-based contrast agent (GBCA)-enhanced magnetic resonance imaging (MRI) at different types of hospitals.

Materials and methods: We retrospectively studied 2,550 patients who underwent MRI at five institutions. We recorded the date and value of each patient's eGFR test. The distribution of eGFR values was compared with that in the general Japanese population.

Results: A total of 84.3% of patients had their eGFRs evaluated before GBCA-enhanced MRI. Of these, 84.7% were evaluated within 3 months before the GBCA-enhanced MRI, and 1.3% were evaluated on the day of the GBCA-enhanced MRI. A total of 87.2% of patients tested had an eGFR of ≥60 ml/min/1.73 m(2); 12.8% had an eGFR of <60 and ≥30 ml/min/1.73 m(2), and no patients had an eGFR of <30 ml/min/1.73 m(2).

Conclusion: The rate of renal function evaluation differed among hospitals. The prevalence of low eGFR values was greater in Juntendo Tokyo Koto Geriatric Medical Center than in the other hospitals, and the prevalence of low eGFR values was greater in patients who underwent GBCA-enhanced MRI than in the general Japanese population.

MeSH terms

  • Aged
  • Contrast Media / adverse effects*
  • Female
  • Gadolinium / adverse effects*
  • Glomerular Filtration Rate / drug effects*
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Nephrogenic Fibrosing Dermopathy / chemically induced
  • Renal Insufficiency / diagnosis
  • Renal Insufficiency / physiopathology*

Substances

  • Contrast Media
  • Gadolinium