Alkaloid and coumarins from the green fruits of Aegle marmelos

Phytochemistry. 2012 Mar:75:108-13. doi: 10.1016/j.phytochem.2011.11.018. Epub 2011 Dec 22.

Abstract

Five (1-5) and 15 known compounds were isolated from the acetone extract of the green fruits of Aegle marmelos. The structure of compounds 1-5, marmesiline (1), 6-(4-acetoxy-3-methyl-2-butenyl)-7-hydroxycoumarin (2), 6-(2-hydroxy-3-hydroxymethyl-3-butenyl)-7-hydroxycoumarin (3), marmelonine (4) and 8-hydroxysmyrindiol (5), were determined on the basis of spectroscopic analyses. Antifungal and antibacterial activities of selected compounds were also evaluated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aegle / chemistry*
  • Alkaloids / chemistry
  • Alkaloids / isolation & purification
  • Alkaloids / pharmacology*
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / pharmacology*
  • Bacteria / drug effects
  • Coumarins / chemistry
  • Coumarins / isolation & purification
  • Coumarins / pharmacology*
  • Dose-Response Relationship, Drug
  • Fruit / chemistry*
  • Fungi / drug effects
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Stereoisomerism
  • Structure-Activity Relationship

Substances

  • Alkaloids
  • Anti-Bacterial Agents
  • Antifungal Agents
  • Coumarins