Henoch-schönlein purpura and elevated hepatitis C virus antibody in a girl with nasopharyngeal diffuse large B-cell lymphoma

Jen-Yin Hou; Hsi-Che Liu; Der-Cherng Liang; Yin-Sum Choi; Chia-Ying Lin; Ting-Chi Yeh

doi:10.1016/j.pedneo.2011.08.009

Henoch-schönlein purpura and elevated hepatitis C virus antibody in a girl with nasopharyngeal diffuse large B-cell lymphoma

Pediatr Neonatol. 2011 Dec;52(6):349-52. doi: 10.1016/j.pedneo.2011.08.009. Epub 2011 Nov 11.

Authors

Jen-Yin Hou¹, Hsi-Che Liu, Der-Cherng Liang, Yin-Sum Choi, Chia-Ying Lin, Ting-Chi Yeh

Affiliation

¹ Division of Pediatric Hematology-Oncology, Mackay Memorial Hospital, Taipei, Taiwan.

PMID: 22192264
DOI: 10.1016/j.pedneo.2011.08.009

Abstract

Henoch-Schönlein purpura (HSP) or hepatitis C virus (HCV) infection was reported in association with malignancies. However, HSP and HCV infection rarely present in pediatric patients with non-Hodgkin's lymphoma. We describe an 8-year-old girl with Stage-IV diffuse large B-cell lymphoma who presented with HSP and elevated HCV antibody titer at diagnosis and at relapse. After treatment, purpura disappeared and HCV antibody titer returned to normal range. There was no recurrence of HSP or elevated HCV antibody during a follow-up of 2 years.

Publication types

Case Reports

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Child
Female
Hepatitis C Antibodies / blood*
Humans
IgA Vasculitis / complications*
Immunoglobulin A / blood
Lymphoma, Large B-Cell, Diffuse / complications*
Lymphoma, Large B-Cell, Diffuse / diagnosis
Lymphoma, Large B-Cell, Diffuse / drug therapy
Nasopharyngeal Neoplasms / complications*
Nasopharyngeal Neoplasms / diagnosis
Nasopharyngeal Neoplasms / drug therapy
Recurrence

Substances

Hepatitis C Antibodies
Immunoglobulin A