Microsurgical management of cerebral parenchymal cysticercosis

Clin Neurol Neurosurg. 2012 May;114(4):385-8. doi: 10.1016/j.clineuro.2011.11.029. Epub 2011 Dec 19.

Abstract

Objective: Microsurgery is an optional way to treat parenchymal neurocysticercosis. The aim of this study is to evaluate the therapeutic efficacy of microsurgery in cerebral parenchymal cysticercosis.

Materials and methods: A retrospective analysis was performed of the clinical data and outcomes of microsurgery in 20 cases of cerebral parenchymal cysticercosis.

Results: All head segments found in cysticercus cysts were removed completely. Total resection of the cystic wall was achieved in 16 cases and subtotal resection in 4 cases. Twelve patients recovered from intracranial hypertension soon after the operation. No novel complications or deaths occurred postoperatively. The patients were followed up for 3 months to 10 years; among them, 14 patients who had epilepsy before surgery were markedly improved and controlled, 4 of 5 patients recovered from hemiparesis within 6 months after surgery, and 2 patients with cerebellar ataxia showed improvement. Two patients were lost to follow-up.

Conclusions: Despite a high rate of misdiagnosis of cerebral parenchymal cysticercosis, microsurgery is associated with satisfactory clinical outcomes in appropriately selected patients.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Animals
  • Anticonvulsants / therapeutic use
  • Child
  • Craniotomy
  • Cysticercus
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Intracranial Hypertension / etiology
  • Magnetic Resonance Imaging
  • Male
  • Microsurgery / methods*
  • Middle Aged
  • Neurocysticercosis / pathology
  • Neurocysticercosis / surgery*
  • Neurosurgical Procedures / methods*
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Young Adult

Substances

  • Anticonvulsants