Changes in response properties of nociceptors and dorsal horn neurons in a murine model of cancer pain

Fiziol Zh (1994). 2011;57(5):75-7.
No abstract available

Publication types

  • Lecture
  • Research Support, N.I.H., Extramural

MeSH terms

  • Action Potentials / drug effects
  • Animals
  • Benzoxazines / therapeutic use
  • Cannabinoids / therapeutic use
  • Dose-Response Relationship, Drug
  • Hot Temperature
  • Hyperalgesia / drug therapy
  • Hyperalgesia / metabolism
  • Hyperalgesia / pathology
  • Hyperalgesia / physiopathology*
  • Mice
  • Morpholines / therapeutic use
  • Naphthalenes / therapeutic use
  • Neoplasms, Experimental / drug therapy
  • Neoplasms, Experimental / metabolism
  • Neoplasms, Experimental / pathology
  • Neoplasms, Experimental / physiopathology*
  • Nerve Fibers, Unmyelinated / pathology
  • Nerve Fibers, Unmyelinated / physiology
  • Nociceptors / pathology*
  • Nociceptors / physiology
  • Pain / drug therapy
  • Pain / metabolism
  • Pain / pathology
  • Pain / physiopathology*
  • Posterior Horn Cells / pathology
  • Posterior Horn Cells / physiopathology*
  • Receptor, Cannabinoid, CB1 / metabolism
  • Receptor, Cannabinoid, CB2 / metabolism

Substances

  • Benzoxazines
  • Cannabinoids
  • Morpholines
  • Naphthalenes
  • Receptor, Cannabinoid, CB1
  • Receptor, Cannabinoid, CB2
  • (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone