[Remodelling extracellular matrix in pineal gland at aging]

Adv Gerontol. 2011;24(3):423-5.
[Article in Russian]

Abstract

Matrix metalloproteinases (MMP) 2 and 9 has been verified in pineal gland, where MMP take part in remodelling extracellular matrix. Descrease of number MMP2 and 9 has been verified in pineal gland of old age and long liver people in comparison with middle age people. Pinealocytes and/or immune cells of pineal gland can synthesize matrix metalloproteinases.

Publication types

  • English Abstract

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Aging / metabolism*
  • Aging / pathology
  • Extracellular Matrix / metabolism*
  • Extracellular Matrix / pathology
  • Humans
  • Immunohistochemistry
  • Lymphocytes / metabolism
  • Matrix Metalloproteinase 2 / metabolism*
  • Matrix Metalloproteinase 9 / metabolism*
  • Middle Aged
  • Pineal Gland / metabolism*
  • Pineal Gland / pathology

Substances

  • Matrix Metalloproteinase 2
  • Matrix Metalloproteinase 9