Abstract
Matrix metalloproteinases (MMP) 2 and 9 has been verified in pineal gland, where MMP take part in remodelling extracellular matrix. Descrease of number MMP2 and 9 has been verified in pineal gland of old age and long liver people in comparison with middle age people. Pinealocytes and/or immune cells of pineal gland can synthesize matrix metalloproteinases.
MeSH terms
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Age Factors
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Aged
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Aged, 80 and over
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Aging / metabolism*
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Aging / pathology
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Extracellular Matrix / metabolism*
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Extracellular Matrix / pathology
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Humans
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Immunohistochemistry
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Lymphocytes / metabolism
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Matrix Metalloproteinase 2 / metabolism*
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Matrix Metalloproteinase 9 / metabolism*
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Middle Aged
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Pineal Gland / metabolism*
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Pineal Gland / pathology
Substances
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Matrix Metalloproteinase 2
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Matrix Metalloproteinase 9