Surgical enucleation of testicular leydigioma in a young child: case report and literature review

J Pediatr Endocrinol Metab. 2011;24(9-10):839-42. doi: 10.1515/jpem.2011.335.

Abstract

Background: The leydigioma is the most frequent interstitial neoplasm of the testis. Clinical symptoms of all leydigioma usually are isosexual precocious pseudo-puberty due to autonomous testosterone overproduction, suppressed gonadotropin levels and a testis mass. Nowadays its therapy is debated.

Design and methods: We report a case of a young child treated in 2008 for a leydigioma of the testis with atypical clinical behavior. Testicular oncologic markers and hormonal profile were assessed.

Results: The patient was treated successfully with organ-confined surgery.

Conclusion: We want to confirm the safety of conservative surgery against radical orchiectomy and review the literature of the last decade on this debated matter.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Humans
  • Leydig Cell Tumor / surgery*
  • Male
  • Organ Sparing Treatments / methods*
  • Testicular Neoplasms / surgery*
  • Testis / surgery*