[Experimental study of Grippferon antiviral activity against Mexican pandemic influenza virus A/H1N1/2009 in vitro]

S Ia Loginova; S V Borisevich; V N Shchukina; G V Borisevich; V P Bondarev; V A Shevtsov

[Experimental study of Grippferon antiviral activity against Mexican pandemic influenza virus A/H1N1/2009 in vitro]

Antibiot Khimioter. 2011;56(5-6):7-10.

[Article in Russian]

Authors

S Ia Loginova, S V Borisevich, V N Shchukina, G V Borisevich, V P Bondarev, V A Shevtsov

PMID: 22145225

Abstract

Analysis of the efficacy of Grippferon vs. the reference drugs Realdiron and Reaferon-EC against the influenza virus A(H1N1)/2009 in susceptible static cell cultures showed that in the concentrations tested it was efficient in inhibition of the virus cytopathic activity and generation of specific hemagglutinin.

Publication types

Comparative Study
English Abstract

MeSH terms

Animals
Antiviral Agents / pharmacology*
Cell Line
Cytopathogenic Effect, Viral / drug effects*
Dogs
Hemagglutination Inhibition Tests
Humans
Influenza A Virus, H1N1 Subtype / drug effects*
Influenza, Human / therapy
Influenza, Human / virology
Inhibitory Concentration 50
Interferon-alpha / pharmacology*
Time Factors
Virus Replication / drug effects*

Substances

Antiviral Agents
Interferon-alpha