SAR-reduced spin-echo-based Bloch-Siegert B(1)(+) mapping: BS-SE-BURST

Magn Reson Med. 2012 Aug;68(2):529-36. doi: 10.1002/mrm.23259. Epub 2011 Nov 30.

Abstract

Fast and accurate B(1)(+) mapping is possible using phase-based Bloch-Siegert (BS) methods. Importantly, the off-resonant pulses needed for BS B(1)(+) mapping methods can easily be implemented in multiple MR sequences. BS-based B(1)(+) mapping has thus been introduced for gradient echo (BS-FLASH), spin-echo (BS-SE), and Carr, Purcell, Meiboom, Gill (CPMG)-based multi-SE and turbo-SE sequences. When using SE and multi-SE/turbo-SE-based BS sequences, however, the high intrinsic specific absorption rates must be considered in clinical situations. This study introduces a fast BS B(1)(+) mapping method based on a SE-BURST sequence (BS-SE-BURST). With SE-BURST sequences, multiple low-magnitude excitation pulses are applied prior to the refocusing pulse. Thus, multiple and different phase-encoded echoes can be acquired per excitation cycle. Compared with a SE sequence, this excitation strategy results in a similar signal-to-noise ratio (SNR) per unit time but with reduced specific absorption rate. The proposed BS-SE-BURST sequence was implemented on a conventional 3 T whole body MRI scanner and applied successfully.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Brain / anatomy & histology*
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Spin Labels

Substances

  • Spin Labels