Research of correlation between the amount of leukocyte in EPS and NIH-CPSI: result from 1242 men in Fangchenggang Area in Guangxi Province

Abstract

Objective: To investigate the correlation between the leukocyte in expressed prostatic secretion (EPS) and National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) in a large Chinese male population.

Materials and methods: Data were collected from 1242 men who participated in the population-based Fangchenggang Area Male Health and Examination Survey (FAMHES), which was carried out in Guangxi, China from September 2009 to December 2009. The severity and symptoms of chronic prostatitis were accessed by the National Institutes of Health Chronic Prostatitis Symptom Index. Meanwhile, the leukocyte in EPS was counted. Demographic information, lifestyle characteristic, and medical history were also obtained through questionnaire.

Results: There was no linear correlation between the leukocyte in EPS and NIH-CPSI scores in all subjects (n=1242) (P>.05). Regardless of whether subjects had prostatitis-like symptoms (n=107), there was no linear correlation between the leukocyte in EPS and NIH-CPSI scores (P>.05). After using chi-square tests linear-by-linear association, there were also no linear correlation between the leukocyte in EPS and NIH-CPSI scores (P>.05).

Conclusion: The results of this study have demonstrated that either in all subjects or in the subjects with prostatitis-like symptoms, there was no linear correlation between the leukocyte in EPS and the severity symptom. So the amount of leukocyte in EPS was unsuitable to apply as the only index of diagnosis, evaluating and observing curative effect. The index should be taken into account for a variety of factors. The improvement of clinical symptom and quality of life were the key points.