Rapid test for identification of a highly transmissible Mycobacterium tuberculosis Beijing strain of sub-Saharan origin

María Isabel Millán-Lou; Henar Alonso; Patricia Gavín; Melissa Hernández-Febles; María Isolina Campos-Herrero; Rodolfo Copado; Fernando Cañas; Kristin Kremer; José Antonio Caminero; Carlos Martín; Sofía Samper

doi:10.1128/JCM.06314-11

Rapid test for identification of a highly transmissible Mycobacterium tuberculosis Beijing strain of sub-Saharan origin

J Clin Microbiol. 2012 Feb;50(2):516-8. doi: 10.1128/JCM.06314-11. Epub 2011 Nov 23.

Authors

María Isabel Millán-Lou¹, Henar Alonso, Patricia Gavín, Melissa Hernández-Febles, María Isolina Campos-Herrero, Rodolfo Copado, Fernando Cañas, Kristin Kremer, José Antonio Caminero, Carlos Martín, Sofía Samper

Affiliation

¹ IIS Aragón, Hospital Universitario Miguel Servet, Zaragoza, Spain. mimillan.iacs@aragon.es

Abstract

The development of a rapid test to identify Mycobacterium tuberculosis Beijing isolates and specifically strain GC1237, coming from a sub-Saharan country, is needed due to its alarming wide spread on Gran Canaria Island (Spain). A rapid test that detects IS6110 present between dnaA and dnaN in the Beijing strains and in a specific site for GC1237 (Rv2180c) has been developed. This test would be a useful tool in the surveillance of subsequent cases.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacteriological Techniques / methods*
DNA Transposable Elements
DNA, Bacterial / genetics
Genes, Bacterial
Humans
Molecular Diagnostic Techniques / methods*
Mycobacterium tuberculosis / genetics
Mycobacterium tuberculosis / isolation & purification*
Spain
Tuberculosis / diagnosis*

Substances

DNA Transposable Elements
DNA, Bacterial