Two new compounds from an endophytic fungus Pestalotiopsis heterocornis

J Asian Nat Prod Res. 2011 Dec;13(12):1069-73. doi: 10.1080/10286020.2011.621422.

Abstract

Two new compounds, 7-hydroxy-5-methoxy-4,6-dimethyl-7-O-α-L-rhamnosyl-phthalide and 7-hydroxy-5-methoxy-4,6-dimethyl-7-O-β-D-glucopyranosyl-phthalide, along with one known and related metabolite 7-hydroxy-5-methoxy-4,6-dimethylphthalide were isolated from the EtOAc extract of fermentation broth of an endophytic fungus Pestalotiopsis heterocornis. The structures of these compounds were elucidated on the basis of spectroscopic methods (UV, IR, HR-ESI-MS, 1D NMR, and 2D NMR).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzofurans / chemistry
  • Benzofurans / isolation & purification*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Xylariales / chemistry*

Substances

  • 7-hydroxy-5-methoxy-4,6-dimethyl-7-O-alpha-L-rhamnosyl-phthalide
  • 7-hydroxy-5-methoxy-4,6-dimethyl-7-O-beta-D-glucopyranosyl-phthalide
  • Benzofurans
  • Glycosides
  • phthalide