Immunosuppressive effects of subglutinol derivatives

ChemMedChem. 2012 Feb 6;7(2):218-22. doi: 10.1002/cmdc.201100409. Epub 2011 Nov 24.

Authors

Won-Gil Lee¹, Woo-Seok Kim, Sung-Gyoo Park, Hyoungsu Kim, Jiyong Hong, Hyojin Ko, Yong-Chul Kim

Affiliation

¹ School of Life Sciences, Gwangju Institute of Science and Technology (GIST), 261 Cheomdan-gwagiro(Oryong- dong), Buk-gu, Gwangju 500-712, Republic of Korea.

PMID: 22114006
DOI: 10.1002/cmdc.201100409

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antigens, CD / metabolism
Antigens, Differentiation, T-Lymphocyte / metabolism
Cells, Cultured
Diterpenes / chemical synthesis
Diterpenes / chemistry*
Diterpenes / pharmacology
Humans
Immunosuppressive Agents / chemical synthesis
Immunosuppressive Agents / chemistry*
Immunosuppressive Agents / pharmacology*
Interleukin-2 / metabolism
Interleukin-2 Receptor alpha Subunit / metabolism
Lectins, C-Type / metabolism
Mice
Pyrones / chemical synthesis
Pyrones / chemistry*
Pyrones / pharmacology
Structure-Activity Relationship
T-Lymphocytes / drug effects*
T-Lymphocytes / immunology
T-Lymphocytes / metabolism

Substances

Antigens, CD
Antigens, Differentiation, T-Lymphocyte
CD69 antigen
Diterpenes
Immunosuppressive Agents
Interleukin-2
Interleukin-2 Receptor alpha Subunit
Lectins, C-Type
Pyrones
subglutinol A
subglutinol B