Cognitive reserve and lifestyle in Spanish individuals with sporadic Alzheimer's disease

Am J Alzheimers Dis Other Demen. 2011 Nov;26(7):542-54. doi: 10.1177/1533317511428150. Epub 2011 Nov 22.

Abstract

Background: Some authors suggest that besides the fundamental components, cognitive reserve (CR) also reflects the influence of a combination of factors that improve mental health.

Method: After obtaining the sociodemographic profile of each participant and evaluating their neurologic and neuropsychologic abilities, first, homogeneity analysis was used as a technique to select variables and reduce the number of categories with similar behavior; then CR construct was identified through a latent class analysis model. It was then possible to categorize participants according to their level in this construct and compare the neuropsychological performance of the subgroups that emerged, using a t test of differences of means for independent samples.

Results: Participants with Alzheimer's disease with low CR scores exhibited significantly greater deficits in measures of memory, attention, and language than patients with high CR.

Conclusions: Our results ratify the effect of higher education, higher professional performance, and ludic activities on CR.

MeSH terms

  • Alzheimer Disease / psychology*
  • Cognitive Reserve*
  • Educational Status
  • Humans
  • Interpersonal Relations
  • Life Style*
  • Neuropsychological Tests
  • Reading
  • Spain