One-step engineering of silver nanoclusters-aptamer assemblies as luminescent labels to target tumor cells

Jinjin Yin; Xiaoxiao He; Kemin Wang; Zhihe Qing; Xu Wu; Hui Shi; Xiaohai Yang

doi:10.1039/c1nr11265a

One-step engineering of silver nanoclusters-aptamer assemblies as luminescent labels to target tumor cells

Nanoscale. 2012 Jan 7;4(1):110-2. doi: 10.1039/c1nr11265a. Epub 2011 Nov 11.

Authors

Jinjin Yin¹, Xiaoxiao He, Kemin Wang, Zhihe Qing, Xu Wu, Hui Shi, Xiaohai Yang

Affiliation

¹ State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha 410082, P. R. China.

PMID: 22080331
DOI: 10.1039/c1nr11265a

Abstract

We reported one-step engineering of intrinsically fluorescent silver nanoclusters-aptamer assemblies that would allow the development of facile and specific luminescent labels for target tumor cell recognition and analysis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aptamers, Nucleotide / chemistry*
Cell Line, Tumor
Fluorescent Dyes / chemistry*
Humans
Metal Nanoparticles / chemistry*
Silver / chemistry*
Spectrometry, Fluorescence

Substances

Aptamers, Nucleotide
Fluorescent Dyes
Silver