Daily vitamin supplementation and hypovitaminosis after obesity surgery

Nutrition. 2012 Apr;28(4):391-6. doi: 10.1016/j.nut.2011.07.012. Epub 2011 Nov 4.

Abstract

Objective: The objective of this study was to determine whether constant daily vitamin supplementation would be sufficient to prevent possible vitamin deficiencies in obese patients undergoing bariatric surgery.

Methods: The study was conducted on 58 men and women (mean age 41 ± 10 y) who underwent Roux-en-Y gastric bypass RYGB and were assessed preoperatively and at 3, 6, and 12 mo after surgery. During the postoperative period, the patients received a multivitamin-mineral supplement on a daily basis.

Results: Serum β-carotene and vitamin C were lower starting from the third postoperative month and continued to be low after 12 mo, and vitamin A was decreased by the sixth month and increased by 12 mo. Vitamin B12 levels were stable up to 6 mo but were decreased by 12 mo. Folic acid levels increased from the third month and remained higher throughout follow-up. One year after surgery there were 19% and 21% increases in the number of patients with vitamin A and vitamin C deficiency, respectively, and a 4% decreased of patients with folic acid deficiency.

Conclusion: Weight loss and improvement in patients' general condition followed surgery, but serum levels of some vitamins were decreased despite the use of a vitamin-mineral supplement. These patients need continuous follow-up and individualized prescription of supplementation after the surgical procedure to prevent and treat vitamin deficiencies.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Avitaminosis / epidemiology
  • Avitaminosis / etiology
  • Avitaminosis / prevention & control*
  • Dietary Supplements*
  • Female
  • Follow-Up Studies
  • Gastric Bypass*
  • Humans
  • Male
  • Middle Aged
  • Obesity / blood
  • Obesity / surgery*
  • Postoperative Complications / epidemiology
  • Postoperative Complications / prevention & control*
  • Prevalence
  • Vitamins / blood
  • Vitamins / pharmacology
  • Vitamins / therapeutic use*

Substances

  • Vitamins