The need for medication reconciliation: a cross-sectional observational study in adult patients

Respir Med. 2011 Oct:105 Suppl 1:S60-6. doi: 10.1016/S0954-6111(11)70013-0.

Abstract

Background: Poor communication of drug therapy at care interface often results in medication errors and adverse drug events. Medication reconciliation has been introduced as a measure to improve continuity of patient care. The aim of this cross-sectional observational study was to evaluate the need for medication reconciliation.

Methods: Comprehensive information on pre-admission therapy was obtained by a research pharmacist for adult medical patients, admitted to a teaching hospital, specialised in pulmonary and allergic diseases, in Slovenia. This information was compared with the in-patient and discharge therapies to identify unintentional discrepancies (medication errors) whose clinical significance was determined by an expert panel reaching consensus.

Results: Most of the included 101 patients were elderly (median age: 73 years) who had multiple medications. Among their in-patient drugs (880), few discrepancies were a medication error (54/654), half of which were judged to be clinically important. A higher rate was observed in the discharge drug therapy (747): 369 of the identified discrepancies (566) were a medication error, over half of which were judged as clinically important. A greater number of pre-admission drugs, poorly taken medication histories and a greater number of medication errors in in-patient therapy predisposed patients to clinically important medication errors in discharge therapy.

Conclusions: This study provided evidence in a small sample of patients on the discontinuity of drug therapy at patient discharge in a hospital in Slovenia and its implications for patient care. To ensure continuity and safety of patient care, medication reconciliation should be implemented throughout a patient's hospital stay.

MeSH terms

  • Aged
  • Continuity of Patient Care* / standards
  • Cross-Sectional Studies
  • Female
  • Humans
  • Lung Diseases / drug therapy
  • Lung Diseases / epidemiology*
  • Male
  • Medical History Taking* / standards
  • Medication Errors / prevention & control*
  • Medication Errors / statistics & numerical data
  • Medication Reconciliation* / standards
  • Patient Discharge / statistics & numerical data
  • Prospective Studies
  • Slovenia / epidemiology