[Evaluation of the intake of a low daily amount of soybeans in oxidative stress, lipid and inflammatory profile, and insulin resistance in patients with metabolic syndrome]

Arq Bras Endocrinol Metabol. 2011 Aug;55(6):399-405. doi: 10.1590/s0004-27302011000600006.
[Article in Portuguese]

Abstract

Objective: Studies show that regular consumption of soybeans reduces the risk of diabetes and cardiovascular diseases. However, most of these studies recommend daily intake of 25 g or more of soy protein, an amount considered high and not well tolerated by patients. The objective of this study was to assess the effect of low daily intake of soybeans in oxidative stress and in components of the metabolic syndrome (MS).

Subjects and methods: Forty individuals with MS were selected and divided into two groups: control group (n = 20) and soybean-treated group (n = 20), which consumed 12.95 g of soy protein for 90 days.

Results: After the treatment, the soybean-treated group showed a decrease in fasting glucose and increase in serum HDL and adiponectin.

Conclusion: Low intake of soy protein for 90 days, besides being well tolerated by the patients, was able to improve several parameters related to the pathophysiology of MS.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Dietary Proteins / administration & dosage*
  • Female
  • Glycine max* / adverse effects
  • Humans
  • Insulin Resistance / physiology
  • Lipid Metabolism / drug effects*
  • Male
  • Metabolic Syndrome / diet therapy*
  • Metabolic Syndrome / metabolism
  • Metabolic Syndrome / prevention & control*
  • Oxidative Stress / drug effects*
  • Statistics, Nonparametric

Substances

  • Dietary Proteins