Selective N-acylation and N-alkylation of biotin

J Org Chem. 2011 Nov 18;76(22):9514-8. doi: 10.1021/jo201615j. Epub 2011 Oct 21.

Abstract

Simple and efficient methodology is presented for the selective acylation and alkylation of biotin at its 3'-nitrogen.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acylation
  • Alkylation
  • Biotin / chemistry*
  • Molecular Structure
  • Stereoisomerism

Substances

  • Biotin