Prospective assessment of transient cocaine-induced psychotic symptoms in a clinical setting

Am J Addict. 2011 Nov-Dec;20(6):535-7. doi: 10.1111/j.1521-0391.2011.00181.x. Epub 2011 Oct 4.

Abstract

Cocaine use is associated with the occurrence of transient psychotic symptoms. Sixteen poly-substance abusers already in treatment, who were diagnosed with crack dependence, were assessed twice: at baseline and after 3 weeks of medical management specifically aimed at cocaine abstinence. The psychotic symptoms were assessed with the French version of the Scale for Assessment of Positive Symptoms-Cocaine-Induced Psychosis (SAPS-CIP). There was a decrease of both cocaine intake and psychotic symptoms at week 3 (Wilcoxon's Z, p < .001 and .028, respectively). Furthermore, there was a significant correlation between psychotic symptoms and dose reduction (r(2) = .49, Spearman's ρ= .613, p < .012).

MeSH terms

  • Adult
  • Cocaine-Related Disorders / complications
  • Cocaine-Related Disorders / psychology*
  • Crack Cocaine / administration & dosage
  • Crack Cocaine / adverse effects*
  • Female
  • Humans
  • Male
  • Prospective Studies
  • Psychiatric Status Rating Scales / statistics & numerical data
  • Psychoses, Substance-Induced / complications
  • Psychoses, Substance-Induced / psychology*
  • Self Medication / statistics & numerical data*

Substances

  • Crack Cocaine