Histopathological analysis of endometrial biopsies in Jos University Teaching Hospital (JUTH), Nigeria. A 5-year critical review

Niger J Med. 2011 Jan-Mar;20(1):151-4.

Abstract

Aims: This study is aimed at giving an insight into the pattern and age distribution of endometrial analysis as seen at Jos University Teaching Hospital.

Methods: This is a retrospective reviewed cases of endometrial biopsies diagnosed between January 1998 to December 2002 in the Histopathological Department ofJos University Teaching Hospital

Results: A review of endometrial biopsies slides from 556 patients revealed that pregnancy related diagnosis was the commonest, representing 302 (54.3%) of histopathological diagnosis, followed by endometrial hyperplasia, accounting for 97 cases (17.5%) and majority of which was categorised as mild hyperplasias. Hydatidiform mole, which ranked third, constituted 58 (10.4%) of the cases studied. Choriocarcinoma was the leading malignancy representing 10 cases (45%) of the malignant tumours and 1.8% of all the endometrial biopsies. Endometrial adenocarcinoma, stromal sarcoma and metastatic cancer constituted 6 (1.0%), 3 (0.5%) and 3 (0.5%), respectively.

Conclusion: The commonest endometrial pattern seen in JUTH over the study period was products of conception which peak in the third decade of life; primary malignancies of the endometrium are uncommon in JUTH and they represented just about 2%.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Biopsy*
  • Child
  • Endometrial Neoplasms / epidemiology
  • Endometrial Neoplasms / pathology*
  • Endometrium / pathology*
  • Female
  • Gestational Trophoblastic Disease / epidemiology
  • Gestational Trophoblastic Disease / pathology*
  • Hospitals, Teaching
  • Humans
  • Incidence
  • Middle Aged
  • Nigeria / epidemiology
  • Pregnancy
  • Retrospective Studies
  • Young Adult