Qadirvirtide

Pak J Pharm Sci. 2011 Oct;24(4):593-5.

Abstract

Qadirvirtide is a fusion inhibitor that may be used as prophylaxis or for the treatment of AIDS. It is a synthetic peptide that is composed of 36 amino acids. Qadirvirtide blocks the entry of HIV genome into human CD4 cells by binding to HR1 as the virus can not come close to the human cell membrane and ultimately fusion of the viral envelope with human cell membrane is prohibited.

Publication types

  • Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / drug therapy
  • Acquired Immunodeficiency Syndrome / prevention & control
  • HIV Envelope Protein gp41 / chemistry
  • HIV Envelope Protein gp41 / metabolism
  • HIV Fusion Inhibitors / metabolism
  • HIV Fusion Inhibitors / pharmacology*
  • HIV Fusion Inhibitors / therapeutic use
  • Humans
  • Peptides / metabolism
  • Peptides / pharmacology*
  • Peptides / therapeutic use

Substances

  • HIV Envelope Protein gp41
  • HIV Fusion Inhibitors
  • Peptides
  • Qadirvirtide