Abstract
The synthesis and photophysical and biological investigation of Ru(II)-polypyridyl stabilized water-soluble, luminescent gold nanoparticles (AuNPs) are described. These structures bind to DNA and undergo rapid cellular uptake, being localized within the cell cytoplasm and nucleus within 4 h.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Nucleus / ultrastructure
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Cytoplasm / ultrastructure
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DNA / metabolism*
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Gold / analysis
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Gold / chemistry*
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HeLa Cells
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Humans
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Luminescence
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Luminescent Agents / analysis*
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Luminescent Agents / chemistry
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Microscopy, Confocal / methods
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Nanoparticles / analysis*
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Nanoparticles / chemistry
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Nanoparticles / ultrastructure
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Organometallic Compounds / analysis*
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Organometallic Compounds / chemistry
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Pyridines / analysis*
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Pyridines / chemistry
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Pyridines / metabolism
Substances
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Luminescent Agents
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Organometallic Compounds
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Pyridines
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Gold
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DNA