Plasma carotenoid concentrations before and after supplementation with astaxanthin in middle-aged and senior subjects

Biosci Biotechnol Biochem. 2011;75(9):1856-8. doi: 10.1271/bbb.110368. Epub 2011 Sep 7.

Abstract

A randomized, double-blind human trial was conducted to assess the effect on the plasma carotenoid concentration of 4- or 12-week astaxanthin supplementation (1 or 3 mg/d) of 20 Japanese middle-aged and senior subjects. The plasma carotenoid concentration was significantly higher after the astaxanthin supplementation than that before in both the 1 mg/d (10 subjects) and 3 mg/d (10 subjects) groups.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Aged
  • Antioxidants / chemistry
  • Antioxidants / metabolism*
  • Biological Availability
  • Carotenoids / blood
  • Chromatography, High Pressure Liquid
  • Dietary Supplements
  • Double-Blind Method
  • Drug Administration Schedule
  • Female
  • Humans
  • Japan
  • Lutein / blood
  • Lycopene
  • Male
  • Middle Aged
  • Oxidative Stress / drug effects
  • Tandem Mass Spectrometry
  • Xanthophylls / administration & dosage
  • Xanthophylls / blood
  • Xanthophylls / pharmacokinetics
  • beta Carotene / blood

Substances

  • Antioxidants
  • Xanthophylls
  • beta Carotene
  • Carotenoids
  • astaxanthine
  • Lycopene
  • Lutein