Abstract
A randomized, double-blind human trial was conducted to assess the effect on the plasma carotenoid concentration of 4- or 12-week astaxanthin supplementation (1 or 3 mg/d) of 20 Japanese middle-aged and senior subjects. The plasma carotenoid concentration was significantly higher after the astaxanthin supplementation than that before in both the 1 mg/d (10 subjects) and 3 mg/d (10 subjects) groups.
Publication types
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Administration, Oral
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Aged
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Antioxidants / chemistry
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Antioxidants / metabolism*
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Biological Availability
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Carotenoids / blood
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Chromatography, High Pressure Liquid
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Dietary Supplements
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Double-Blind Method
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Drug Administration Schedule
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Female
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Humans
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Japan
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Lutein / blood
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Lycopene
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Male
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Middle Aged
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Oxidative Stress / drug effects
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Tandem Mass Spectrometry
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Xanthophylls / administration & dosage
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Xanthophylls / blood
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Xanthophylls / pharmacokinetics
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beta Carotene / blood
Substances
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Antioxidants
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Xanthophylls
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beta Carotene
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Carotenoids
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astaxanthine
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Lycopene
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Lutein