One-pot synthesis of pyrrolo[1,2-a]quinoxalines

Org Biomol Chem. 2011 Nov 7;9(21):7351-7. doi: 10.1039/c1ob05936j. Epub 2011 Sep 6.

Abstract

A transition metal-free process for the regioselective synthesis of pyrrolo[1,2-a]quinoxalines under mild conditions in one-pot is described. The reaction afforded a variety of products in good to excellent yields. Indolo[1,2-a]quinoxalines were also synthesized from indole-2-carboxamides under the same conditions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Models, Molecular
  • Molecular Structure
  • Pyrroles / chemical synthesis*
  • Pyrroles / chemistry
  • Quinoxalines / chemical synthesis*
  • Quinoxalines / chemistry
  • Stereoisomerism

Substances

  • Pyrroles
  • Quinoxalines
  • pyrrolo(1,2-a)quinoxaline