Rapid, transient, and proportional activation of σ(B) in response to osmotic stress in Listeria monocytogenes

Marta Utratna; Iain Shaw; Emily Starr; Conor P O'Byrne

doi:10.1128/AEM.05732-11

Rapid, transient, and proportional activation of σ(B) in response to osmotic stress in Listeria monocytogenes

Appl Environ Microbiol. 2011 Nov;77(21):7841-5. doi: 10.1128/AEM.05732-11. Epub 2011 Sep 2.

Authors

Marta Utratna¹, Iain Shaw, Emily Starr, Conor P O'Byrne

Affiliation

¹ Bacterial Stress Response Group, Microbiology, School of Natural Sciences, National University of Ireland, Galway, Galway, Ireland.

Abstract

The osmotic activation of sigma B (σ(B)) in Listeria monocytogenes was studied by monitoring expression of four known σ(B)-dependent genes, opuCA, lmo2230, lmo2085, and sigB. Activation was found to be rapid, transient, and proportional to the magnitude of the osmotic stress applied, features that underpin the adaptability of this pathogen.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Proteins / biosynthesis*
Gene Expression Profiling
Gene Expression Regulation, Bacterial*
Listeria monocytogenes / drug effects*
Listeria monocytogenes / genetics
Listeria monocytogenes / physiology*
Osmotic Pressure*
Sigma Factor / biosynthesis*
Stress, Physiological*

Substances

Bacterial Proteins
SigB protein, Bacteria
Sigma Factor