Total synthesis of (±)-chloranthalactone A

Guizhou Yue; Li Yang; Changchun Yuan; Xiaoling Jiang; Bo Liu

doi:10.1021/ol202190b

Total synthesis of (±)-chloranthalactone A

Org Lett. 2011 Oct 7;13(19):5406-8. doi: 10.1021/ol202190b. Epub 2011 Sep 2.

Authors

Guizhou Yue¹, Li Yang, Changchun Yuan, Xiaoling Jiang, Bo Liu

Affiliation

¹ Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China.

PMID: 21888336
DOI: 10.1021/ol202190b

Abstract

A total synthesis of (±)-chloranthalactone A was completed. It features substrate-controlled epoxidation of ketone and highly diastereoselective intramolecular cyclopropanation to construct the cis, trans-3/5/6 tricyclic skeleton.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Heterocyclic Compounds, 4 or More Rings / chemical synthesis*
Lactones / chemical synthesis*
Models, Molecular
Molecular Structure

Substances

Heterocyclic Compounds, 4 or More Rings
Lactones
chloranthalactone A