Cost-effectiveness of tobacco control policies in Vietnam: the case of personal smoking cessation support

Addiction. 2012 Mar;107(3):658-70. doi: 10.1111/j.1360-0443.2011.03632.x. Epub 2011 Nov 1.

Abstract

Aims: To examine the cost-effectiveness of personal smoking cessation support in Vietnam.

Design, setting and participants: We followed-up the population aged 15 years and over in 2006 to model the costs and health gains associated with five interventions: physician brief advice; nicotine replacement therapy (patch and gum); bupropion; and varenicline. Threshold analysis was undertaken to determine the price levels of pharmaceuticals for the interventions to be cost-effective. A multi-state life table model was constructed such that the interventions affect the smoking cessation behaviour of the age cohorts, and the resulting smoking prevalence defines their health outcomes. A health-care perspective was employed.

Measurements: Cost-effectiveness is measured in 2006 Vietnamese Dong (VND) per disability-adjusted life year (DALY) averted. We adopted the World Health Organization thresholds of being 'cost-effective' if less than three times gross domestic product (GDP) per capita (VND 34,600,000) and 'very cost-effective' if less than GDP per capita (VND 11,500,000).

Findings: The cost-effectiveness result of physician brief advice was VND 1,742,000 per DALY averted (international dollars 543), which was 'very cost-effective'. Varenicline dominated bupropion and nicotine-replacement therapies, although it did not fall within the range of being 'cost-effective' under different scenarios. The threshold analysis revealed that prices of pharmaceuticals must be substantially lower than the levels from other countries if pharmacological therapies are to be cost-effective in Vietnam.

Conclusions: Physician brief advice is a cost-effective intervention and should be included in the priority list of tobacco control policy in Vietnam. Pharmacological therapies are not cost-effective, and so they are not recommended in Vietnam at this time unless pharmaceuticals could be produced locally at substantially lower costs in the future.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Cutaneous
  • Administration, Oral
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antidepressive Agents, Second-Generation / economics
  • Antidepressive Agents, Second-Generation / therapeutic use
  • Benzazepines / economics
  • Benzazepines / therapeutic use
  • Bupropion / economics
  • Bupropion / therapeutic use
  • Cost-Benefit Analysis
  • Female
  • Health Policy / economics*
  • Humans
  • Male
  • Middle Aged
  • Nicotinic Agonists / economics
  • Nicotinic Agonists / therapeutic use
  • Patient Acceptance of Health Care / statistics & numerical data
  • Quinoxalines / economics
  • Quinoxalines / therapeutic use
  • Smoking / economics
  • Smoking Cessation / economics*
  • Smoking Prevention*
  • Social Support
  • Tobacco Use Cessation Devices / economics*
  • Varenicline
  • Vietnam
  • Young Adult

Substances

  • Antidepressive Agents, Second-Generation
  • Benzazepines
  • Nicotinic Agonists
  • Quinoxalines
  • Bupropion
  • Varenicline