Characteristics of suicide attempts in anorexia and bulimia nervosa: a case-control study

PLoS One. 2011;6(8):e23578. doi: 10.1371/journal.pone.0023578. Epub 2011 Aug 12.

Abstract

Objective: Compared to other eating disorders, anorexia nervosa (AN) has the highest rates of completed suicide whereas suicide attempt rates are similar or lower than in bulimia nervosa (BN). Attempted suicide is a key predictor of suicide, thus this mismatch is intriguing. We sought to explore whether the clinical characteristics of suicidal acts differ between suicide attempters with AN, BN or without an eating disorders (ED).

Method: Case-control study in a cohort of suicide attempters (n = 1563). Forty-four patients with AN and 71 with BN were compared with 235 non-ED attempters matched for sex, age and education, using interview measures of suicidal intent and severity.

Results: AN patients were more likely to have made a serious attempt (OR = 3.4, 95% CI 1.4-7.9), with a higher expectation of dying (OR = 3.7,95% CI 1.1-13.5), and an increased risk of severity (OR = 3.4,95% CI 1.2-9.6). BN patients did not differ from the control group. Clinical markers of the severity of ED were associated with the seriousness of the attempt.

Conclusion: There are distinct features of suicide attempts in AN. This may explain the higher suicide rates in AN. Higher completed suicide rates in AN may be partially explained by AN patients' higher desire to die and their more severe and lethal attempts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anorexia Nervosa / psychology*
  • Bulimia Nervosa / parasitology*
  • Case-Control Studies
  • Cohort Studies
  • Diagnostic and Statistical Manual of Mental Disorders
  • Educational Status
  • Female
  • Humans
  • Interview, Psychological
  • Logistic Models
  • Male
  • Middle Aged
  • Risk Factors
  • Suicide / psychology*
  • Suicide / statistics & numerical data
  • Suicide, Attempted / psychology*
  • Suicide, Attempted / statistics & numerical data
  • Young Adult