The paper presents a case of pregnancy childbirth and postpartum of a 47-year-old woman with secondary infertility and obstetric history. In vitro fertilization with oocyte derived from a 21-year donor (IVF-OD) was performed due to premature ovarian failure and age of the patient. The treatment resulted in unifetal pregnancy complicated by among others: hypertension, cardiac problems, varicose veins in the lower limbs, elevated concentration of bile acids and anxiety neurosis. A healthy newborn was delivered at 37 hbd by cesarean section. Due to the development of techniques of assisted reproduction, pregnancies of perimenopausal women will pose a growing problem in modern obstetrics.