Cerebral schistosomiasis due to Schistosoma haematobium confirmed by PCR analysis of brain specimen

Kentaro Imai; Tomohiko Koibuchi; Takashi Kumagai; Takuya Maeda; Yoshio Osada; Nobuo Ohta; Michiko Koga; Hitomi Nakamura; Toshiyuki Miura; Aikichi Iwamoto; Takeshi Fujii

doi:10.1128/JCM.01073-11

Cerebral schistosomiasis due to Schistosoma haematobium confirmed by PCR analysis of brain specimen

J Clin Microbiol. 2011 Oct;49(10):3703-6. doi: 10.1128/JCM.01073-11. Epub 2011 Aug 17.

Authors

Kentaro Imai¹, Tomohiko Koibuchi, Takashi Kumagai, Takuya Maeda, Yoshio Osada, Nobuo Ohta, Michiko Koga, Hitomi Nakamura, Toshiyuki Miura, Aikichi Iwamoto, Takeshi Fujii

Affiliation

¹ Department of Infectious Diseases and Applied Immunology, Research Hospital of The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

Abstract

The case of a 25-year-old Japanese male who had cerebral schistosomiasis caused by Schistosoma haematobium is reported here. Although serum antibody tests showed a cross-reaction with other helminths and no ova were excreted in urine or feces, the existence of Schistosoma haematobium in the brain was confirmed by PCR analysis.

Publication types

Case Reports

MeSH terms

Adult
Animals
Antibodies, Helminth / blood
Asian People
Brain / diagnostic imaging
Brain / pathology*
Central Nervous System Parasitic Infections / diagnosis*
Central Nervous System Parasitic Infections / parasitology
Central Nervous System Parasitic Infections / pathology
Cross Reactions
Feces / parasitology
Histocytochemistry
Humans
Magnetic Resonance Imaging
Male
Microscopy
Molecular Diagnostic Techniques / methods*
Parasitology / methods*
Polymerase Chain Reaction / methods*
Radiography
Schistosoma haematobium / genetics
Schistosoma haematobium / isolation & purification*
Schistosomiasis haematobia / diagnosis*
Schistosomiasis haematobia / parasitology
Schistosomiasis haematobia / pathology
Urine / parasitology

Substances

Antibodies, Helminth