microRNAs as peripheral blood biomarkers of cardiovascular disease

Valeria Di Stefano; Germana Zaccagnini; Maurizio C Capogrossi; Fabio Martelli

doi:10.1016/j.vph.2011.08.001

microRNAs as peripheral blood biomarkers of cardiovascular disease

Vascul Pharmacol. 2011 Oct;55(4):111-8. doi: 10.1016/j.vph.2011.08.001. Epub 2011 Aug 6.

Authors

Valeria Di Stefano¹, Germana Zaccagnini, Maurizio C Capogrossi, Fabio Martelli

Affiliation

¹ Molecular Cardiology Laboratory, IRCCS-Policlinico San Donato, Via Morandi 30, San Donato Milanese, 20097 Milan, Italy.

PMID: 21846509
DOI: 10.1016/j.vph.2011.08.001

Abstract

A host of studies have established essential roles for microRNAs in cardiovascular development and disease. Moreover, the discovery of stable microRNAs in bodily fluids indicated their potential as non-invasive biomarkers. In this review, we summarize the current studies describing microRNAs in blood cells or serum/plasma, as potential biomarkers of cardiovascular disease.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Biomarkers / blood
Blood Cells / metabolism
Cardiovascular Diseases / blood*
Cardiovascular Diseases / metabolism
Cardiovascular Diseases / physiopathology
Humans
MicroRNAs / blood*
MicroRNAs / metabolism

Substances

Biomarkers
MicroRNAs