Nickel-catalyzed tetramerization of alkynes: synthesis and structure of octatetraenes

Tsun-Cheng Wu; Jheng-Jhih Chen; Yao-Ting Wu

doi:10.1021/ol201814q

Nickel-catalyzed tetramerization of alkynes: synthesis and structure of octatetraenes

Org Lett. 2011 Sep 16;13(18):4794-7. doi: 10.1021/ol201814q. Epub 2011 Aug 15.

Authors

Tsun-Cheng Wu¹, Jheng-Jhih Chen, Yao-Ting Wu

Affiliation

¹ Department of Chemistry, National Cheng Kung University, No. 1 Ta-Hsueh Road, 70101 Tainan, Taiwan.

PMID: 21842836
DOI: 10.1021/ol201814q

Abstract

In the presence of a catalytic system comprised of NiBr(2)(dppe) and Zn, arylacetylenes undergo tetramerization to form linear octatetraenes, generally in good to excellent yields. The structure of the coupling products was verified by X-ray crystallography.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkynes / chemistry*
Catalysis
Crystallography, X-Ray
Cyclooctanes / chemical synthesis*
Cyclooctanes / chemistry*
Models, Molecular
Molecular Structure
Nickel / chemistry*
Organometallic Compounds / chemistry*
Stereoisomerism
Zinc / chemistry

Substances

Alkynes
Cyclooctanes
Organometallic Compounds
Nickel
Zinc