PURPOSE: The purpose of this paper is to examine the experiences of poor drug users and sellers who remained in New Orleans during Hurricane Katrina in 2005 to identify their special needs and the unique challenges they present to disaster management. DESIGN/METHODOLOGY/APPROACH: Semi-structured, open-ended interviews were conducted with 119 poor, predominantly African-American, drug users and sellers. Their stories in their own words provide a mosaic of drug-related experiences from the period immediately preceding the storm through evacuation and reveal the motivations behind their behaviors. FINDINGS: Many drug users placed partying, maintaining their habits, and making money ahead of personal safety and evacuation. Drug use and sales led many not to evacuate before the storm, to use drugs in congregate shelters, to avoid shelters, to roam through flooded debris-strewn streets, to loot stores and homes of drug dealers, and to use violence or the threat of violence to achieve their drug-related aims. ORIGINALITY/VALUE: During a disaster, many poor drug users place risks on themselves, their families, their communities and ultimately on rescue workers. The conclusion presents pragmatic and humanitarian guidelines for successfully addressing this additional challenge. The recommendations are consistent with other suggestions concerning the special needs of indigent populations.