Antioxidant and urease inhibitory C-glycosylflavonoids from Celtis africana

J Asian Nat Prod Res. 2011 Sep;13(9):799-804. doi: 10.1080/10286020.2011.593171.

Abstract

Two new C-glycosylflavonoids celtisides A (1) and B (2) have been isolated from n-butanol-soluble fraction of Celtis africana, along with five known C-glycosylflavonoids vitexin (3), orientin (4), isoswertiajaponin (5), isoswertisin (6), and 2″-O-rhamnosyl vitexin (7) reported for the first time from this species. Their structures were assigned from 1D and 2D NMR spectra. These compounds were investigated for biological activities and showed significant antioxidant and urease inhibitory activities.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology*
  • Apigenin / chemistry
  • Apigenin / isolation & purification*
  • Apigenin / pharmacology*
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification*
  • Flavonoids / pharmacology*
  • Glucosides / chemistry
  • Glucosides / isolation & purification*
  • Glucosides / pharmacology*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology*
  • Humans
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Saudi Arabia
  • Ulmaceae / chemistry*
  • Urease / antagonists & inhibitors*

Substances

  • Antioxidants
  • Flavonoids
  • Glucosides
  • Glycosides
  • celtiside A
  • celtiside B
  • Apigenin
  • vitexin
  • Urease
  • orientin