Spinocerebellar ataxia type 2 (SCA2) is associated with TDP-43 pathology

Acta Neuropathol. 2011 Sep;122(3):375-8. doi: 10.1007/s00401-011-0862-7. Epub 2011 Aug 10.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adaptor Proteins, Signal Transducing / metabolism
  • Brain / metabolism*
  • Brain / pathology*
  • DNA-Binding Proteins / metabolism*
  • Family Health
  • Female
  • Humans
  • Inclusion Bodies / metabolism
  • Inclusion Bodies / pathology
  • Male
  • Middle Aged
  • Neurons / pathology*
  • Peptides / metabolism
  • Sequestosome-1 Protein
  • Spinocerebellar Ataxias* / genetics
  • Spinocerebellar Ataxias* / metabolism
  • Spinocerebellar Ataxias* / pathology

Substances

  • Adaptor Proteins, Signal Transducing
  • DNA-Binding Proteins
  • Peptides
  • SQSTM1 protein, human
  • Sequestosome-1 Protein
  • polyglutamine