[Sterols of marine bryozoan Bugula neritina from the South China Sea]

Zhong Yao Cai. 2011 Feb;34(2):180-3.
[Article in Chinese]

Abstract

Objective: To study the sterol constituents of Bugula neritina from the South China Sea.

Methods: The alcohol extract of Bugula neritina was purified by silica gel column and Sephadex LH-20 column chromatography, and structures of the isolated compounds were identified by spectroscopic analysis and comparison with those of literatures.

Results: Ten sterols were isolated and identified from the petroleum ether fraction of alcohol extract of B. neritina L.:Cholest-4-en-3-one(I); cholesterol(II);3beta,5alpha,9alpha-trihydroxy-(22E,24R)-ergosta-7,22-dien-6-one(III); 24-methyl-5alpha-cholesta-7,22-diene-3beta,5,6beta-triol(IV); 3beta-Hydroxy-7-methoxy-Cholesta-5-en(V);5alpha, 8alpha-epidioxy-(22E,24R)-ergosta-6, 22-dien-3beta-ol(VI); 3beta-hydroxycholest-5-en-7-one (VII); and 6beta-hydroxy-cholest-4-en-3-one(VIII); Cholesta-5-ene-3beta,7beta-diol(IX); Cholesta-5,22(E)-dien-3beta,7alpha-diol(X).

Conclusion: Compounds IV-X were isolated from Bugula neritina for the first time.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bryozoa / chemistry*
  • China
  • Cholestenones / chemistry
  • Cholestenones / isolation & purification
  • Chromatography, Thin Layer
  • Materia Medica / chemistry*
  • Molecular Structure
  • Oceans and Seas
  • Sterols / chemistry
  • Sterols / isolation & purification*

Substances

  • 7-oxopetrosterol
  • Cholestenones
  • Materia Medica
  • Sterols
  • cholest-4-en-3-one