Efficient preparation and biological evaluation of a novel multivalency bifunctional chelator for 64Cu radiopharmaceuticals

Chemistry. 2011 Sep 5;17(37):10222-5. doi: 10.1002/chem.201101894. Epub 2011 Aug 4.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Chelating Agents / chemical synthesis*
  • Chelating Agents / chemistry
  • Copper Radioisotopes / chemistry
  • Dipeptides
  • Disease Models, Animal
  • Humans
  • Integrin alphaVbeta3 / metabolism
  • Mice
  • Molecular Structure
  • Peptides, Cyclic / chemical synthesis
  • Peptides, Cyclic / chemistry
  • Positron-Emission Tomography
  • Radiopharmaceuticals / chemical synthesis*
  • Radiopharmaceuticals / chemistry
  • Xenograft Model Antitumor Assays

Substances

  • Chelating Agents
  • Copper Radioisotopes
  • Dipeptides
  • Integrin alphaVbeta3
  • Peptides, Cyclic
  • Radiopharmaceuticals
  • cyclo(Arg-Gly-Asp-Tyr-Lys)
  • alanyltyrosine