Synthesis of mono, bis-2-(2-arylideneaminophenyl) indole azomethines as potential antimicrobial agents

Abstract

A series of mono and bis 2-2-(arylidineaminophenyl)indole azomethines have been synthesized by a condensation reaction of 2-(2-amino phenyl) indole with various mono and diketones R-CO-R(l) /R-CO-X-CO-R(l) (1:1/2:1 ratio) in ethanol media. The synthesized azomethines were characterized via IR, (1)H-NMR, (13)C-NMR, MS and elemental analysis. The antimicrobial activity of these compounds against different bacteria and fungi was also evaluated.