A facile synthesis of sugar-pyrazole derivatives

Arasappan Hemamalini; Subbiah Nagarajan; Thangamuthu Mohan Das

doi:10.1016/j.carres.2011.06.019

A facile synthesis of sugar-pyrazole derivatives

Carbohydr Res. 2011 Sep 27;346(13):1814-9. doi: 10.1016/j.carres.2011.06.019. Epub 2011 Jun 28.

Authors

Arasappan Hemamalini¹, Subbiah Nagarajan, Thangamuthu Mohan Das

Affiliation

¹ Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India.

PMID: 21784420
DOI: 10.1016/j.carres.2011.06.019

Abstract

A facile synthesis of sugar-pyrazole derivatives has been accomplished by condensation of sugar-chalcone with hydrazine hydrate under neutral conditions resulting in yields of 70-85%. The products are characterized by FTIR and NMR spectroscopy and by elemental analysis. The β-anomeric forms for these derivatives were assigned by NMR spectroscopy.

MeSH terms

Carbohydrates / chemistry*
Glycosides / chemistry*
Ketones / chemistry*
Magnetic Resonance Spectroscopy
Molecular Structure
Pyrazoles / chemistry*
Spectroscopy, Fourier Transform Infrared

Substances

Carbohydrates
Glycosides
Ketones
Pyrazoles
pyrazole