Neuroscience: Imprinting in the brain

Nature. 2011 Jul 20;475(7356):299-300. doi: 10.1038/475299a.

Abstract

A gene is considered to be imprinted if only the copy inherited from the mother or from the father is expressed throughout life. But one imprinted gene, Dlk1, disobeys this rule during postnatal neurodevelopment.

Publication types

  • News
  • Comment

MeSH terms

  • Aging / genetics
  • Aging / metabolism
  • Animals
  • Animals, Newborn / growth & development
  • Animals, Newborn / metabolism*
  • Astrocytes / metabolism*
  • Calcium-Binding Proteins
  • Embryo, Mammalian / metabolism
  • Female
  • Genomic Imprinting*
  • Intercellular Signaling Peptides and Proteins / genetics
  • Intercellular Signaling Peptides and Proteins / metabolism*
  • Male
  • Mice
  • Neural Stem Cells / metabolism*
  • Neurogenesis*
  • Olfactory Bulb / cytology
  • Stem Cell Niche / cytology*
  • Stem Cell Niche / metabolism

Substances

  • Calcium-Binding Proteins
  • Dlk1 protein, mouse
  • Intercellular Signaling Peptides and Proteins