Three new phytoecdysteroids containing a furan ring from the roots of Achyranthes bidentata Bl

Qiu-Hong Wang; Liu Yang; Hai Jiang; Zhi-Bin Wang; Bing-You Yang; Hai-Xue Kuang

doi:10.3390/molecules16075989

Three new phytoecdysteroids containing a furan ring from the roots of Achyranthes bidentata Bl

Molecules. 2011 Jul 18;16(7):5989-97. doi: 10.3390/molecules16075989.

Authors

Qiu-Hong Wang¹, Liu Yang, Hai Jiang, Zhi-Bin Wang, Bing-You Yang, Hai-Xue Kuang

Affiliation

¹ Key Laboratory of Chinese Materia Medica, Heilongjiang University of Chinese Medicine), Ministry of Education, No. 24 HePing Road, XiangFang District, Harbin 150040, China.

Abstract

Three new phytoecdysteroid compounds, named niuxixinsterone A (1), B (2) and C (3) with acetal functions in the side-chain were isolated from Achyranthes bidentata Bl. The structures were established as (20R,22R,24S)-20-O,22-O-(5'-hydroxymethyl)-furfurylidene-2β,3β,14α,25-tetrahydroxy-5β-ergost-7-en-6-one (1), (20R,22R)-20-O,22-O-(5'-hydroxymethyl)-furfurylidene-2β,3β,25-trihydroxy-14β-methyl-18-nor-5β-cholesta-7,12-dien-6-one (2) and (20R,22R,25R)-20-O,22-O-(5'-hydroxymethyl)-furfurylidene-2β, 3β,5β,14α,26-pentahydroxycholest-7-en-6-one (3) by means of spectroscopic evidence.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Achyranthes / chemistry*
Ecdysteroids / chemistry*
Furans / chemistry*
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Roots / chemistry*

Substances

Ecdysteroids
Furans