Abstract
We describe 58 adult patients with melioidosis in Cambodia (2007-2010). Diabetes was the main risk factor (59%); 67% of infections occurred during the rainy season. Bloodstream infection was present in 67% of patients, which represents 12% of all bloodstream infections. The case-fatality rate was 52% and associated with inappropriate empiric treatment.
MeSH terms
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Adolescent
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Adult
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Aged
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Burkholderia pseudomallei* / drug effects
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Burkholderia pseudomallei* / isolation & purification
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Cambodia / epidemiology
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Carbapenems / administration & dosage
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Carbapenems / therapeutic use
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Cephalosporins / administration & dosage
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Cephalosporins / therapeutic use
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Diabetes Mellitus, Type 2 / physiopathology
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Diagnostic Errors*
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Doxycycline / administration & dosage
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Doxycycline / therapeutic use
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Female
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Humans
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Male
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Melioidosis / diagnosis*
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Melioidosis / drug therapy
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Melioidosis / epidemiology
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Melioidosis / microbiology*
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Melioidosis / mortality
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Microbial Sensitivity Tests
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Middle Aged
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Risk Factors
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Sulfamethoxazole / administration & dosage
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Sulfamethoxazole / therapeutic use
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Survival Rate
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Trimethoprim / administration & dosage
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Trimethoprim / therapeutic use
Substances
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Carbapenems
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Cephalosporins
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Trimethoprim
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Sulfamethoxazole
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Doxycycline