Channelopathies: summary of the hot topic keynotes session

Neurotoxicology. 2011 Oct;32(5):661-5. doi: 10.1016/j.neuro.2011.06.002. Epub 2011 Jul 2.

Abstract

The "Hot Topic Keynotes: Channelopathies" session of the 26th International Neurotoxicology Conference brought together toxicologists studying interactions of environmental toxicants with ion channels, to review the state of the science of channelopathies and to discuss the potential for interactions between environmental exposures and channelopathies. This session presented an overview of chemicals altering ion channel function and background about different channelopathy models. It then explored the available evidence that individuals with channelopathies may or may not be more sensitive to effects of chemicals.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Channelopathies / chemically induced*
  • Channelopathies / metabolism*
  • Congresses as Topic / trends
  • Drug-Related Side Effects and Adverse Reactions / chemically induced
  • Drug-Related Side Effects and Adverse Reactions / metabolism
  • Environmental Exposure / adverse effects*
  • Humans
  • Ion Channel Gating / physiology